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Issued: London, UK

Statement: Zantac (ranitidine) litigation – Russell and Hughes cases

GSK plc (LSE/NYSE: GSK) today confirmed it has reached two confidential settlements in cases filed in California State Court with Mr. John Russell, resolving his bladder cancer case, and with Ms. Annette Hughes, resolving her colorectal case. GSK does not admit any liability in either settlement. The cases will now be dismissed as to GSK.

Since 2019, following the 16 epidemiological studies looking at human data regarding the use of ranitidine, the scientific consensus is that there is no consistent or reliable evidence that ranitidine increases the risk of any cancer.

GSK will continue to vigorously defend itself and manage this litigation in the best interests of the company and shareholders.

About GSK

GSK is a global biopharma company with a purpose to unite science, technology, and talent to get ahead of disease together. Find out more at gsk.com.

Cautionary statement regarding forward-looking statements

GSK cautions investors that any forward-looking statements or projections made by GSK, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Such factors include, but are not limited to, those described under Item 3.D “Risk factors” in GSK’s Annual Report on Form 20-F for 2023, and GSK’s Q2 Results for 2024.